产品货号:
Z34860
中文名称:
Ms CD105/Endoglin/ENG Purified抗体
英文名称:
Anti-Ms CD105/Endoglin/ENG Purified Antibody (Clone#MJ7/18)
产品规格:
0.1mg(C100)
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-Ms CD105/Endoglin/ENG Purified Antibody (Clone#MJ7/18) |
指标别名 | CD105;END;Endoglin;ENG;HHT1;ORW;ORW1 |
克隆性 | Monoclonal |
检验物种 | mouse |
应用范围 | FCM,IP,WB,IHC-F |
基因名称 | Eng |
克隆号 | MJ7/18 |
抗体来源 | Rat |
免疫原 | Inflamed mouse skin.The rat monoclonal antibody MJ7/18 reacts with an extracellular epitope of CD105 (Endoglin),a 90kDa type I homodimerizing membrane glycoprotein expressed on vascular endothelial cells (small and large vessels),activated monocytes and tissue macrophages,stromal cells of certain tissues including bone marrow,pre-B lymphocytes in fetal marrow and erythroid precursors in fetal and adult bone marrow. |
计算分子量 | 70kDa |
成分 | Phosphate buffered saline (PBS),pH7.4,15mM sodium azide |
纯化方式 | Purified by protein-G affinity chromatography. |
浓度 | 1mg/mL |
产品形态 | 溶液 |
保存条件 | Store at 2~8℃.Do not freeze. |
背景资料 | CD105 (endoglin) is a homodimeric transmembrane glycoprotein serving in presence of TGFbetaR-2 as a receptor for TGFbeta-1 and TGFbeta-3.CD105 is highly expressed on endothelial cells and promotes angiogenesis during wound healing,infarcts and in a wide range of tumours and its gene expression is stimulated by hypoxia.CD105 prevents apoptosis in hypoxic endothelial cells and also antagonises the inhibitory effects of TGFbeta-1 on vascular endothelial cell growth and migration.Normal cellular levels of CD105 are required for formation of new blood vessels. |
Uniprot ID | Q63961 |
基因名全称 | Endoglin |
蛋白名全称 | Endoglin |
推荐稀释比 | Flow cytometry:1~4μg/mL. |
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